QSensor QSX 341 Amine Coupling
Immobilizing biomolecules in a functional manner on a sensor surface is a successful way of analyzing bio- molecular interactions.
Q-Sense Amine Coupling Sensor, QSX 341, enables covalent immobilization of biomolecules via their amino groups (-NH2) to a PEG coating activated with N-hydroxysuccinimide (NHS) (Figure 1). This allows for fast immobilization reactions with the non-reacted NHS groups easily washed off to expose the zero-back- ground PEG coating.
- Delivered with NHS molecules bound
- Fast and easy immobilization reactions
- Any molecule of interest with free amine group Usage include antibody optimization, protein-protein interactions and probing of conformational changes
|Typically ships within||8 weeks|
|Surface Chemistry||Poly (ethylene glycol) (PEG) 3 nm coating and functionalization with a density of 1014 NHS molecules/cm2.|
|Sensor Surface||Glass (SiO2)|
|Binding||The free NHS molecules on the sensor are replaced with a covalent linkage to the protein via its free amine groups.|
|Specificity||The zero-background PEG coating eliminates non-specific binding.|
|Shelf Life||Stable > 8 weeks from package date when stored in original vacuum-bag at -20 to -80 °C. Opened sensors should be stored in vacuum desiccator or in 100% nitrogen environment.|
|Usage||Direct mounting into the instrument from the box without prior cleaning (possibly blow with N2 gas for dust removal). The ove non-reacted NHS molecules.|
Note: QSensors are developed and produced to provide you with stable, reliable and reproducible data. Full performance is ensured through extensive quality controls, and guaranteed for one-time use according to the recommendations.